SCHEMBL28530940

SCHEMBL28530940

Nc1ccc(O)c(-n2nccn2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
PDE10A Q9Y233 1/20 0.42
KDM4E B2RXH2 4/20 0.38
CASP1 P29466 3/20 0.38
ALDH1A1 P00352 3/20 0.38
ALOX15 P16050 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CYP3A4 P08684 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
TNF P01375 1/20 0.38
HSPD1 P10809 1/20 0.38
THRB P10828 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTGS2 P35354 1/20 0.38
KDR P35968 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28524455 0.84 CASP1 (0.42) MEN1KMT2ACA1CA2PDE10A
SCHEMBL29793409 0.84 CASP1 (0.42) MEN1KMT2ACA1CA2PDE10A
SCHEMBL27479321 0.79 LMNA (0.38) MEN1KMT2ACA1CA2KDM4E
SCHEMBL14320723 0.76 CYP3A4 (0.46) MEN1KMT2ACA1CA2KDM4E
SCHEMBL28533584 0.76 IDO1 (0.54) MEN1KMT2ACA1CA2CASP1
SCHEMBL908266 0.76 LMNA (0.61) MEN1KMT2AKDM4EALDH1A1ALOX15
SCHEMBL1353507 0.76 ALDH1A1 (0.55) MEN1KMT2APDE10AKDM4ECASP1
SCHEMBL14320316 0.76 IDO1 (0.34) MEN1KMT2AKDM4ECASP1ALDH1A1
SCHEMBL2627231 0.76 NPC1 (0.36) MEN1KMT2AKDM4ECASP1ALDH1A1
SCHEMBL28533724 0.76 ABAT (0.38) CA1CA2KDM4EALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114714724-B Hot melt adhesive transfer film and preparation method thereof 云阳金田塑业有限公司 2023-11-17 CN claimed
CN-114714724-A Hot melt adhesive transfer film and preparation method thereof 云阳金田塑业有限公司 2022-07-08 CN claimed
CN-114714724-B Hot melt adhesive transfer film and preparation method thereof 云阳金田塑业有限公司 2023-11-17 CN disclosed
CN-114714724-A Hot melt adhesive transfer film and preparation method thereof 云阳金田塑业有限公司 2022-07-08 CN disclosed
CN-108842932-B High-adhesion polyolefin anti-adhesion film and preparation method thereof 江苏优珀斯材料科技有限公司 2021-03-19 CN disclosed