Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
| ▸ | SELL | P14151 | 1/20 | 0.48 |
| ▸ | SELP | P16109 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.48 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2271181 | 0.88 | GAA (0.60) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL22022887 | 0.86 | MEN1 (0.76) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL5696409 | 0.85 | ALDH1A1 (0.63) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL22022912 | 0.85 | ALDH1A1 (0.57) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL9080159 | 0.84 | ALDH1A1 (0.61) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL9080504 | 0.82 | LPAR1 (0.50) | ALDH1A1SRD5A2KDM4EKDM4CLMNA | |
| SCHEMBL2271165 | 0.82 | KDM4E (0.62) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL8044298 | 0.81 | ALDH1A1 (0.60) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL8768524 | 0.81 | ALDH1A1 (0.59) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL9079780 | 0.81 | KDM4E (0.67) | MEN1KMT2AGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |