Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | PLK1 | P53350 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | DVL1 | O14640 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420661 | 0.87 | HTT (0.55) | PLK1SMN1; SMN2HTTNR1H4 | |
| SCHEMBL8419001 | 0.85 | KDM4E (0.57) | ALDH1A1KDM4EPKMPLK1SMN1; SMN2 | |
| SCHEMBL8418953 | 0.82 | ALDH1A1 (0.60) | ALDH1A1KDM4ESMN1; SMN2HTTKMT2A | |
| SCHEMBL8422577 | 0.82 | HTT (0.54) | KDM4ESMN1; SMN2HTTNR1H4AKR1C2 | |
| SCHEMBL14075341 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4EPKMSMN1; SMN2NR1H4 | |
| SCHEMBL9082681 | 0.81 | MEN1 (0.57) | ALDH1A1KDM4EPKMSMN1; SMN2NR1H4 | |
| SCHEMBL8038280 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4EPKMPLK1SMN1; SMN2 | |
| SCHEMBL8422575 | 0.79 | SMN1; SMN2 (0.50) | ALDH1A1KDM4EPLK1SMN1; SMN2HTT | |
| SCHEMBL8420658 | 0.78 | SMN1; SMN2 (0.52) | ALDH1A1KDM4EPLK1SMN1; SMN2HTT | |
| SCHEMBL8041236 | 0.78 | PLK1 (0.61) | ALDH1A1KDM4EPKMPLK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |