Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 16/20 | 0.62 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.47 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007127 | 0.88 | PLA2G1B (0.66) | PLA2G1BPLA2G2APLA2G10PLA2G5PLA2G2E | |
| SCHEMBL14584006 | 0.78 | PLA2G1B (0.51) | PLA2G1BPLA2G2APLA2G5PLA2G2E | |
| SCHEMBL7018369 | 0.77 | PLA2G1B (1.00) | PLA2G1BPLA2G2APLA2G10PLA2G5PLA2G2E | |
| SCHEMBL7102348 | 0.77 | PLA2G1B (0.84) | PLA2G1BPLA2G2APLA2G10PLA2G5PLA2G2E | |
| SCHEMBL7011452 | 0.76 | PTGS2 (0.51) | PLA2G1B | |
| SCHEMBL7006970 | 0.72 | PLA2G1B (0.71) | PLA2G1BPLA2G2APLA2G10PLA2G5PLA2G2E | |
| SCHEMBL7016187 | 0.70 | PLA2G1B (0.69) | PLA2G1BPLA2G2APLA2G10PLA2G5PLA2G2E | |
| SCHEMBL8352190 | 0.68 | PLA2G1B (0.61) | PLA2G1BPLA2G2APLA2G10PLA2G5PLA2G2E | |
| SCHEMBL9082881 | 0.68 | PLA2G1B (0.51) | PLA2G1BPLA2G2APLA2G10PLA2G5PLA2G2E | |
| SCHEMBL14614219 | 0.68 | PLA2G1B (0.76) | PLA2G1BPLA2G2APLA2G5PLA2G2E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996003383-A1 | INDOLIZINE sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |