Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.52 |
| ▸ | GABRP | O00591 | 4/20 | 0.52 |
| ▸ | GABRD | O14764 | 4/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.52 |
| ▸ | GABRE | P78334 | 4/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.52 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PDE5A | O76074 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386471 | 0.89 | KMT2A (0.47) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2953007 | 0.80 | GABRA1 (0.56) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9081597 | 0.76 | GABRA1 (0.48) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2945211 | 0.76 | GABRA1 (0.60) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2951128 | 0.74 | GABRA1 (0.57) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2953162 | 0.74 | GABRA1 (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2953165 | 0.74 | GABRA1 (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28819880 | 0.71 | GABRA1 (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL5333503 | 0.70 | KDM4E (0.47) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4273795 | 0.70 | GABRP (0.60) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484793-A | NERVOUS SYSTEM DISORDERS; COGNITION ACTIVATORS; ALZHEIMER*S DISEASE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1996-01-16 | — | — | US | disclosed |