⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL323856 | 0.79 | — | — | |
| SCHEMBL5596441 | 0.71 | — | — | |
| SCHEMBL1975990 | 0.71 | LMNA (0.44) | — | |
| SCHEMBL1258355 | 0.71 | — | — | |
| SCHEMBL3041677 | 0.69 | ABCC4 (0.46) | — | |
| SCHEMBL127297 | 0.69 | — | — | |
| SCHEMBL3968169 | 0.67 | ABCC4 (0.45) | — | |
| SCHEMBL28157601 | 0.67 | ABCC4 (0.45) | — | |
| SCHEMBL6120452 | 0.67 | ABCC4 (0.45) | — | |
| SCHEMBL515176 | 0.67 | LMNA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523460-A | ANTICHOLESTEROL AGENTS | FUJIREBIO INC. (JP) | 1996-06-04 | — | — | US | claimed |
| US-5393780-A | Anticholesterol, antilipemic agents | FUJIREBIO INC. (JP) | 1995-02-28 | — | — | US | claimed |
| EP-0616999-A2 | 4-Fluorobiphenyl derivatives | FUJIREBIO Inc. (JP) | 1994-09-28 | — | — | EP | claimed |
| EP-0617000-A2 | 4-Fluorobiphenyl derivatives | FUJIREBIO Inc. (JP) | 1994-09-28 | — | — | EP | claimed |
| JP-6329581-A | — | — | None | — | — | JP | disclosed |
| JP-6329582-A | — | — | None | — | — | JP | disclosed |
| US-5523460-A | ANTICHOLESTEROL AGENTS | FUJIREBIO INC. (JP) | 1996-06-04 | — | — | US | disclosed |
| US-5523460-A | ANTICHOLESTEROL AGENTS | FUJIREBIO INC. (JP) | 1996-06-04 | — | — | US | disclosed |
| US-5393780-A | Anticholesterol, antilipemic agents | FUJIREBIO INC. (JP) | 1995-02-28 | — | — | US | disclosed |
| US-5393780-A | Anticholesterol, antilipemic agents | FUJIREBIO INC. (JP) | 1995-02-28 | — | — | US | disclosed |
| JP-H06329581-A | 4-FLUOROBIPHENYL DERIVATIVE | FUJIREBIO INC | 1994-11-29 | — | — | JP | disclosed |
| JP-H06329582-A | 4-FLUOROBIPHENYL DERIVATIVE | FUJIREBIO INC | 1994-11-29 | — | — | JP | disclosed |
| EP-0616999-A2 | 4-Fluorobiphenyl derivatives | FUJIREBIO Inc. (JP) | 1994-09-28 | — | — | EP | disclosed |
| EP-0616999-A2 | 4-Fluorobiphenyl derivatives | FUJIREBIO Inc. (JP) | 1994-09-28 | — | — | EP | disclosed |
| EP-0617000-A2 | 4-Fluorobiphenyl derivatives | FUJIREBIO Inc. (JP) | 1994-09-28 | — | — | EP | disclosed |
| EP-0617000-A2 | 4-Fluorobiphenyl derivatives | FUJIREBIO Inc. (JP) | 1994-09-28 | — | — | EP | disclosed |