Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378024 | 0.78 | KMT2A (0.53) | PKMKMT2ARAB9AMEN1POLB | |
| SCHEMBL19754000 | 0.78 | MAPK1 (0.50) | KMT2APOLBGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL8762582 | 0.76 | KMT2A (0.63) | PKMKMT2ARAB9AMEN1POLB | |
| SCHEMBL17059408 | 0.76 | ALDH1A1 (0.49) | KMT2ARAB9APOLBGAAATM | |
| SCHEMBL3381147 | 0.74 | ACHE (0.61) | PKMKMT2ARAB9AMEN1GAA | |
| SCHEMBL19742516 | 0.73 | L3MBTL1 (0.47) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL30279891 | 0.73 | L3MBTL1 (0.47) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL30539159 | 0.72 | ALDH1A1 (0.60) | KMT2AMEN1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL836536 | 0.72 | ALDH1A1 (0.60) | KMT2AMEN1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL3656114 | 0.71 | MAPK1 (0.57) | PKMKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816051-B2 | Conjugated biological molecules and their preparation | POLYTHERICS LIMITED (GB) | 2014-08-26 | — | — | US | disclosed |
| US-20110182855-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | POLYTHERICS LIMITED (GB) | 2011-07-28 | — | — | US | disclosed |
| EP-2277550-A1 | Conjugated biological molecules and their preparation | Polytherics Limited (GB) | 2011-01-26 | — | — | EP | disclosed |
| US-20060210526-A1 | polyoxyethylene glycol-protein conjugate linked via linking group | ABZENA (CAMBRIDGE) LIMITED (GB) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182855-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | F13B, ZYX, F13A1 | PKM 2623/4885KMT2A 4253/4885RAB9A 1758/4885 |
| US-20060210526-A1 | polyoxyethylene glycol-protein conjugate linked via linking group | F13A1, F13B, SSB | PKM 3131/4885KMT2A 4148/4885RAB9A 2519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.