Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL908478 | 0.87 | PKM (0.75) | HSD11B1KMT2APKMPAX8ALDH1A1 | |
| SCHEMBL6908652 | 0.85 | HSD11B1 (1.00) | HSD11B1KMT2APKMCES2CES1 | |
| SCHEMBL27933117 | 0.83 | HSD11B1 (1.00) | HSD11B1KMT2APAX8LMNAMAPT | |
| SCHEMBL7861808 | 0.82 | HTT (0.57) | HSD11B1KMT2APKMALDH1A1MAPT | |
| SCHEMBL4477185 | 0.81 | CES1 (0.70) | HSD11B1KMT2ACES2CES1ALDH1A1 | |
| SCHEMBL28538245 | 0.81 | HSD11B1 (0.91) | HSD11B1PKMCES2CES1ALDH1A1 | |
| SCHEMBL29275338 | 0.80 | HSD11B1 (0.81) | HSD11B1KMT2APAX8ALDH1A1GSK3B | |
| SCHEMBL29275340 | 0.79 | HSD11B1 (1.00) | HSD11B1KMT2APAX8ALDH1A1MAPT | |
| SCHEMBL29275367 | 0.79 | HSD11B1 (1.00) | HSD11B1KMT2APAX8MAPK1 | |
| SCHEMBL27933084 | 0.79 | HSD11B1 (1.00) | HSD11B1KMT2APAX8ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197108-B | Preparation method of gamma-ketosulfone compound | 南华大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-115197108-A | Preparation method of gamma-ketosulfone compound | 南华大学 | 2022-10-18 | — | — | CN | disclosed |