Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 14/20 | 0.72 |
| ▸ | TACR1 | P25103 | 1/20 | 0.64 |
| ▸ | TACR3 | P29371 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16915248 | 0.89 | NMBR (0.58) | NMBRTACR1TACR3MAPTGAA | |
| SCHEMBL18251830 | 0.89 | NMBR (0.70) | NMBRTACR1TACR3MAPTGAA | |
| SCHEMBL6013894 | 0.87 | NMBR (0.61) | NMBRTACR1TACR3MAPTGAA | |
| SCHEMBL6020259 | 0.87 | NMBR (0.58) | NMBRTACR1TACR3MAPTGAA | |
| SCHEMBL6020248 | 0.87 | CTSL (0.67) | NMBRTACR1TACR3MAPTSMN1; SMN2 | |
| SCHEMBL4930789 | 0.86 | NMBR (0.58) | NMBRTACR1TACR3MAPT | |
| SCHEMBL4930779 | 0.86 | NMBR (0.58) | NMBRTACR1TACR3MAPT | |
| SCHEMBL18255299 | 0.86 | NMBR (0.56) | NMBRTACR1TACR3MAPTGAA | |
| SCHEMBL18251829 | 0.86 | NMBR (0.65) | NMBRTACR1MAPTGAAHTT | |
| SCHEMBL29354625 | 0.85 | NMBR (0.56) | NMBRTACR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556853-A | THIOL PROTEASE INHIBITORS, TREATMENT OF OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0655447-A1 | Epoxysuccinic acid derivatives | Takeda Chemical Industries, Ltd. (JP) | 1995-05-31 | — | — | EP | disclosed |