Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 10/20 | 0.58 |
| ▸ | TACR1 | P25103 | 1/20 | 0.55 |
| ▸ | TACR3 | P29371 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4930789 | 1.00 | NMBR (0.58) | NMBRTACR1TACR3HDAC3HDAC1 | |
| SCHEMBL6013894 | 0.90 | NMBR (0.61) | NMBRTACR1TACR3MAPT | |
| SCHEMBL3795866 | 0.87 | NMBR (0.68) | NMBRLMNAMAPT | |
| SCHEMBL9088692 | 0.86 | NMBR (0.72) | NMBRTACR1TACR3MAPT | |
| SCHEMBL30074815 | 0.84 | KMT2A (0.58) | NMBRTACR1MAPT | |
| SCHEMBL6020259 | 0.84 | NMBR (0.58) | NMBRTACR1TACR3LMNAMAPT | |
| SCHEMBL6020248 | 0.83 | CTSL (0.67) | NMBRTACR1TACR3LMNAMAPT | |
| SCHEMBL16915248 | 0.82 | NMBR (0.58) | NMBRTACR1TACR3MAPT | |
| SCHEMBL8226837 | 0.82 | NMBR (0.52) | NMBRTACR1TACR3LMNAMAPT | |
| SCHEMBL119372 | 0.81 | ALOX15 (0.56) | NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | S*BIO PTE LTD. (SG) | 2008-03-20 | — | — | US | disclosed |
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | S*BIO PTE LTD. (SG) | 2008-03-20 | — | — | US | disclosed |
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | S*BIO PTE LTD. (SG) | 2008-03-20 | — | — | US | disclosed |
| EP-1685094-A4 | ACYLUREA CONNECTED AND SULFONYLUREA CONNECTED HYDROXAMATES | S BIO PTE LTD (SG) | 2007-08-22 | — | — | EP | disclosed |
| EP-1685094-A1 | ACYLUREA CONNECTED AND SULFONYLUREA CONNECTED HYDROXAMATES | S*Bio Pte Ltd (SG) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005040101-A1 | ACYLUREA CONNECTED AND SULFONYLUREA CONNECTED HYDROXAMATES | S*BIO PTE LTD (SG) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | HDAC1, HDAC3, HDAC4 | NMBR 3240/4885TACR1 4185/4885TACR3 3504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.