Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 12/20 | 0.61 |
| ▸ | TACR1 | P25103 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TACR3 | P29371 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3795866 | 0.91 | NMBR (0.68) | NMBRGAAMAPTHTT | |
| SCHEMBL4930789 | 0.90 | NMBR (0.58) | NMBRTACR1MAPTTACR3 | |
| SCHEMBL4930779 | 0.90 | NMBR (0.58) | NMBRTACR1MAPTTACR3 | |
| SCHEMBL4888176 | 0.89 | NMBR (0.56) | NMBRTACR1TACR3 | |
| SCHEMBL9088692 | 0.87 | NMBR (0.72) | NMBRTACR1GAAMAPTHTT | |
| SCHEMBL16915248 | 0.87 | NMBR (0.58) | NMBRTACR1GAAMAPTHTT | |
| SCHEMBL6020259 | 0.86 | NMBR (0.58) | NMBRTACR1GAAMAPTHTT | |
| SCHEMBL6020248 | 0.86 | CTSL (0.67) | NMBRTACR1GAAMAPTHTT | |
| SCHEMBL850319 | 0.86 | ALOX15 (0.56) | NMBR | |
| SCHEMBL119594 | 0.86 | ALOX15 (0.56) | NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635877-A2 | SPECIFIC HIGH-RELAXIVITY CONJUGATE COMPOUNDS FOR MAGNETIC RESONANCE IMAGING | GUERBET (FR) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004112839-A2 | SPECIFIC HIGH-RELAXIVITY CONJUGATE COMPOUNDS FOR MAGNETIC RESONANCE IMAGING | GUERBET (FR) | 2004-12-29 | — | — | WO | disclosed |