Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 4/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310230 | 0.84 | ALDH1A1 (0.44) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8315189 | 0.75 | ALDH1A1 (0.44) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9333312 | 0.74 | TP53 (0.40) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8315473 | 0.74 | ALDH1A1 (0.48) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8315198 | 0.69 | TBXAS1 (0.40) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9133332 | 0.69 | TBXAS1 (0.39) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8313649 | 0.67 | ALDH1A1 (0.47) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8316035 | 0.67 | MEN1 (0.47) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8311271 | 0.65 | KMT2A (0.48) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10445963 | 0.62 | XIAP (0.41) | KDM4EALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482937-A | ANTIALLERGENS AND PLATELET ACTIVATING FACTOR FOR TREATMENT OF INFLAMMATION | EISAI CO., LTD. (JP) | 1996-01-09 | — | — | US | disclosed |