Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315189 | 0.83 | ALDH1A1 (0.44) | TP53ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL8310230 | 0.75 | ALDH1A1 (0.44) | TP53ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL9089232 | 0.74 | KDM4E (0.47) | TP53ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL8311271 | 0.74 | KMT2A (0.48) | TP53ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL8315668 | 0.68 | ALDH1A1 (0.46) | TP53ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL8316470 | 0.67 | NPSR1 (0.40) | TP53ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL8315473 | 0.65 | ALDH1A1 (0.48) | TP53ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL8316035 | 0.63 | MEN1 (0.47) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8315198 | 0.60 | TBXAS1 (0.40) | TP53ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL23620086 | 0.59 | P2RX4 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304553-A | Antiallergens; platelet activating factor inhibitor | EISAI CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |