Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999689 | 0.82 | AGTR1 (0.39) | — | |
| SCHEMBL8999691 | 0.82 | AGTR1 (0.39) | — | |
| SCHEMBL8999603 | 0.78 | AGTR1 (0.48) | — | |
| SCHEMBL8999634 | 0.78 | AGTR1 (0.48) | — | |
| SCHEMBL9091313 | 0.78 | — | — | |
| SCHEMBL8999683 | 0.77 | L3MBTL1 (0.42) | MITF | |
| SCHEMBL8999769 | 0.76 | AGTR1 (0.39) | — | |
| SCHEMBL8999604 | 0.76 | AGTR1 (0.38) | — | |
| SCHEMBL28010023 | 0.75 | LMNA (0.43) | MITF | |
| SCHEMBL28010959 | 0.75 | LMNA (0.43) | MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571925-A | HORMONES INHIBITORS FOR HYPOTENSIVE AGENTS | ELI LILLY AND COMPANY (US) | 1996-11-05 | — | — | US | disclosed |
| US-5563278-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0438869-B1 | Improvements in and relating to angiotensin II antagonists | LILLY CO ELI (US) | 1994-12-14 | — | — | EP | disclosed |
| US-5312936-A | Hypotensive agents | ELI LILLY AND COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| US-5073566-A | Hypotensive agents | ELI LILLY AND COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0438869-A1 | Improvements in and relating to angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1991-07-31 | — | — | EP | disclosed |