Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | ATM | Q13315 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589936 | 0.81 | ATM (0.58) | L3MBTL1ATMMEN1KMT2AMAPT | |
| SCHEMBL9541710 | 0.81 | ATM (0.61) | L3MBTL1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL6313952 | 0.78 | L3MBTL1 (0.54) | L3MBTL1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL9091970 | 0.78 | L3MBTL1 (0.54) | L3MBTL1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL8589748 | 0.77 | L3MBTL1 (0.53) | L3MBTL1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL3670113 | 0.77 | ATM (0.73) | L3MBTL1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL3670110 | 0.77 | ATM (0.73) | L3MBTL1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL8593543 | 0.77 | ATM (0.59) | L3MBTL1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL8592466 | 0.76 | L3MBTL1 (0.52) | L3MBTL1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL8593599 | 0.76 | L3MBTL1 (0.52) | L3MBTL1ATMMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521220-A | Acyclic ethylenediamine derivatives | PFIZER INC. (US) | 1996-05-28 | — | — | US | disclosed |