Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404056 | 0.89 | CHRM2 (0.58) | L3MBTL1ATMALDH1A1GAAMAPT | |
| SCHEMBL4538523 | 0.89 | CHRM2 (0.58) | L3MBTL1ATMALDH1A1GAAMAPT | |
| SCHEMBL20988035 | 0.88 | ATM (0.63) | L3MBTL1ATMALDH1A1GAAMAPT | |
| SCHEMBL9092986 | 0.78 | L3MBTL1 (0.64) | L3MBTL1ATMALDH1A1GAAMAPT | |
| SCHEMBL8931140 | 0.75 | ATM (0.59) | L3MBTL1ATMALDH1A1GAAMAPT | |
| SCHEMBL27002023 | 0.74 | ALDH1A1 (0.49) | L3MBTL1ATMALDH1A1GAAMAPT | |
| SCHEMBL27002169 | 0.74 | ALDH1A1 (0.49) | L3MBTL1ATMALDH1A1GAAMAPT | |
| SCHEMBL9965797 | 0.74 | ATM (0.67) | L3MBTL1ATMALDH1A1GAAMAPT | |
| SCHEMBL4901405 | 0.73 | L3MBTL1 (0.61) | L3MBTL1ATMALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL841799 | 0.73 | ATM (0.65) | L3MBTL1ATMALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497257-A1 | 2,5-BIS-DIAMINE-[1,4] BENZOQUINONE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE, A PROCESS FOR THEIR PREPARATION AND INTERMEDIATES THEREFOR | Alma Mater Studiorum -Universita' di Bologna (IT) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087035-A1 | 2,5-BIS-DIAMINE-'1,4! BENZOQUINONE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE A PROCESS FOR THEIR PREPARATION AND INTERMEDIATES THEREFOR | ALMA MATER STUDIORUM-UNIVERSITA' DI BOLOGNA (IT) | 2003-10-23 | — | — | WO | disclosed |