Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.61 |
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | PRCP | P42785 | 6/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9092197 | 0.94 | DRD2 (0.58) | DRD2HTR1AGRIN1GRIN2BHTR2A | |
| SCHEMBL9092795 | 0.88 | GMNN (0.57) | DRD2HTR1AGRIN1GRIN2BHTR2A | |
| SCHEMBL9093188 | 0.88 | MEN1 (0.59) | DRD2HTR1APRCPGRIN1GRIN2B | |
| SCHEMBL11790517 | 0.87 | DRD2 (0.63) | DRD2HTR1AGRIN1GRIN2BHTR2A | |
| SCHEMBL8105223 | 0.82 | HTR1A (0.62) | DRD2HTR1ADRD4ADRA1ADRD3 | |
| SCHEMBL9092161 | 0.81 | SLC18A3 (0.59) | DRD2HTR1AGRIN1GRIN2BGRIN2D | |
| SCHEMBL10438172 | 0.81 | SLC18A3 (0.59) | DRD2PRCPGRIN1GRIN2BSLC18A3 | |
| SCHEMBL4796352 | 0.80 | HTR1A (0.61) | DRD2HTR1ADRD4ADRA1ADRD3 | |
| SCHEMBL9092128 | 0.78 | HTR1A (0.56) | DRD2HTR1AGRIN1GRIN2BGRIN2D | |
| SCHEMBL11021738 | 0.77 | DRD2 (0.75) | DRD2HTR1ADRD4HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589486-A | ANTIHYPOXIC OR ANTIISCHEMIC AGENTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1996-12-31 | — | — | US | disclosed |
| EP-0642497-A1 | NOVEL N-HYDROXYALKYL-SUBSTITUTED 1,2,3,6-TETRAHYDROPYRIDINE AND PIPERIDINE DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993011107-A1 | NOVEL N-HYDROXYALKYL-SUBSTITUTED 1,2,3,6-TETRAHYDROPYRIDINE AND PIPERIDINE DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1993-06-10 | — | — | WO | disclosed |