Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18426840 | 0.83 | CYP1A2 (0.48) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL9009627 | 0.81 | NCF1 (0.50) | NCF1CYP1A2NOS2BACE1CA12 | |
| Bromide SCHEMBL1866312 | 0.81 | CYP1A2 (0.47) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL28818196 | 0.79 | S1PR3 (0.47) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL9094486 | 0.79 | S1PR3 (0.47) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL1261380 | 0.78 | CYP1A2 (0.48) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL1459296 | 0.78 | NCF1 (0.41) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL827081 | 0.77 | CYP1A2 (0.52) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL30106721 | 0.77 | NCF1 (0.46) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL10020390 | 0.77 | ALDH1A1 (0.53) | NCF1CYP1A2NOS2BACE1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016061-B1 | ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-10 | — | — | EP | claimed |
| US-20150368278-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2015-12-24 | — | — | US | disclosed |
| US-8957049-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2015-02-17 | — | — | US | disclosed |
| US-20110172186-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. | 2011-07-14 | — | — | US | disclosed |
| EP-2282742-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | Infinity Pharmaceuticals, Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009126691-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC (US) | 2009-10-15 | — | — | WO | disclosed |
| US-7285375-B2 | Photosensitive composition, photosensitive lithography plate and method for producing lithography plate | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2007-10-23 | — | — | US | disclosed |
| US-20070020555-A1 | Photosensitive composition, photosensitive lithography plate and method for producing lithography plate | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2007-01-25 | — | — | US | disclosed |
| US-7009055-B2 | such as (methyl-sulfonyl)methyl bromo-quinoline by treatment of dibromomethyl bromo-quinoline with sodium methanesulfinate in solvent; chemical intermediates in production of phosphodiesterase inhibitors | MERCK & CO., INC. (US) | 2006-03-07 | — | — | US | disclosed |
| US-20040176604-A1 | Preparation of sulfonyl quinoline | XU FENG (US) | 2004-09-09 | — | — | US | disclosed |
| WO-2003010137-A1 | PREPARATION OF SULFONYL QUINOLINE | MERCK & CO., INC. (US) | 2003-02-06 | — | — | WO | disclosed |
| EP-0016061-B1 | ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-10 | — | — | EP | disclosed |
| EP-0016061-A4 | ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS. | DU PONT (US) | 1981-08-27 | — | — | EP | disclosed |
| EP-0016061-A1 | ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS. | DU PONT (US) | 1980-10-01 | — | — | EP | disclosed |
| WO-1980000040-A1 | ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS | DU PONT (US) | 1980-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176604-A1 | Preparation of sulfonyl quinoline | STS, SULT2A1, BRD7 | NCF1 3187/4885CYP1A2 1883/4885NOS2 3844/4885 |
| US-20110172186-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, ASAH1 | NCF1 2864/4885CYP1A2 207/4885NOS2 1783/4885 |
| US-20150368278-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, ASAH1 | NCF1 2864/4885CYP1A2 207/4885NOS2 1783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.