Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | YES1 | P07947 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040315 | 0.81 | CA2 (0.67) | CA2KMT2ATDP1GSK3B | |
| SCHEMBL898510 | 0.81 | CA2 (0.67) | CA2KMT2AMEN1MAPTPOLB | |
| SCHEMBL10549629 | 0.81 | CA2 (0.67) | CA2KMT2AMEN1KDM4EMAPT | |
| Pemoline Dione SCHEMBL7864463 | 0.80 | CA2 (1.00) | CA2ESR2KMT2AMEN1KDM4E | |
| Pemoline Dione SCHEMBL11265294 | 0.78 | CA2 (0.96) | CA2ESR2KMT2AMEN1KDM4E | |
| SCHEMBL9094464 | 0.76 | CA2 (0.51) | CA2KMT2AMEN1KDM4EMAPT | |
| SCHEMBL9096555 | 0.72 | CA2 (0.46) | CA2KMT2AKDM4EMAPTCYP3A4 | |
| SCHEMBL10761058 | 0.72 | CA2 (0.59) | CA2MAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11040411 | 0.72 | CA2 (0.64) | CA2KDM4EGSK3B | |
| SCHEMBL10758325 | 0.70 | CA2 (0.58) | CA2POLBAKT1CYP19A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498621-A | Oxazolidinedione hypoglycemic agents | PFIZER INC. (US) | 1996-03-12 | — | — | US | disclosed |
| EP-0428312-A2 | Oxazolidinedione hypoglycemic agents | PFIZER INC. (US) | 1991-05-22 | — | — | EP | disclosed |