Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9096643 | 0.86 | RORC (0.38) | EPHX2CYP1A1CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL9093938 | 0.82 | EPHX2 (0.37) | EPHX2CYP1A1CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL9097387 | 0.77 | ADRB2 (0.41) | KDM4EHPGDLMNAHSD17B10ALDH1A1 | |
| SCHEMBL9095407 | 0.77 | ADRB2 (0.36) | KDM4EGLAGAAHPGDHSD17B10 | |
| SCHEMBL9094019 | 0.77 | ADRB2 (0.33) | ADRB2 | |
| Hydrochloric Acid SCHEMBL9094427 | 0.76 | ADRB2 (0.36) | KDM4EHPGDHSD17B10RORCALDH1A1 | |
| SCHEMBL9095909 | 0.74 | ADRB2 (0.38) | ALDH1A1DRD2ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL9236348 | 0.73 | ADRB2 (0.37) | KDM4EGLAGAAHPGDHSD17B10 | |
| SCHEMBL9096487 | 0.73 | ADRB2 (0.36) | KDM4EGAAMAPTHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9094189 | 0.73 | ADRB2 (0.36) | KDM4EHSD17B10ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576324-A | Quinoline derivatives or salt thereof and remedy for cardiac diseases containing the same | KOWA CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0638571-A1 | QUINOLINE DERIVATIVE OR SALT THEREOF AND REMEDY FOR CARDIAC DISEASES CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |