Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9095614 | 0.73 | CA2 (0.32) | CA2CA4CA1CA12CA9 | |
| SCHEMBL19475597 | 0.72 | CA2 (0.44) | CA2ALDH1A1CA4CA1CA12 | |
| SCHEMBL1939405 | 0.70 | CA2 (0.35) | CA2CA1CA12CA9 | |
| SCHEMBL9094131 | 0.69 | CA2 (0.39) | CA2ALDH1A1CA1FAAHCA12 | |
| Hydrochloric Acid SCHEMBL9256738 | 0.69 | CA2 (0.39) | CA2CA1FAAHCA12CA9 | |
| SCHEMBL24979121 | 0.68 | LOXL2 (0.39) | CA2CA1CA12CA9 | |
| SCHEMBL9260724 | 0.68 | LOXL2 (0.36) | CA2 | |
| SCHEMBL21962509 | 0.67 | CA2 (0.36) | CA2CA4CA1CA12CA9 | |
| SCHEMBL5516839 | 0.65 | CA2 (0.39) | CA2CA1CA12CA9 | |
| SCHEMBL22509130 | 0.64 | RAB9A (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519040-A | Substituted thiazole sulfonamides as antiglaucoma agents | ALLERGAN (US) | 1996-05-21 | — | — | US | disclosed |
| WO-1995029904-A1 | SUBSTITUTED THIAZOLE SULFONAMIDES AS ANTIGLAUCOMA AGENTS | ALLERGAN (US) | 1995-11-09 | — | — | WO | disclosed |