SCHEMBL909643

SCHEMBL909643

Nc1n[nH]c(C(F)(F)F)n1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.37
LMNA P02545 1/20 0.37
RAB9A P51151 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 4/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 2/20 0.34
CYP1A2 P05177 1/20 0.34
MAPT P10636 5/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
GAA P10253 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALPL P05186 1/20 0.32
AOC3 Q16853 2/20 0.32
NPSR1 Q6W5P4 1/20 0.30
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9712691 0.75 L3MBTL1 (0.48) POLBRAB9AKMT2AALDH1A1KDM4E
SCHEMBL10208108 0.70 POLB (0.37) POLBLMNARAB9ACYP2C19KMT2A
SCHEMBL20301699 0.70 CSNK2A1 (0.38) POLBLMNARAB9ACYP2C19KMT2A
SCHEMBL688580 0.70 LMNA (0.37) POLBLMNARAB9ACYP2C19KMT2A
SCHEMBL8220963 0.70 CSNK2A2 (0.38) POLBLMNARAB9ACYP2C19KMT2A
SCHEMBL5924179 0.69 L3MBTL1 (0.38) POLBRAB9AKMT2AALDH1A1KDM4E
SCHEMBL21339906 0.68 AOC3 (0.52) LMNARAB9AKMT2AALDH1A1KDM4E
SCHEMBL11640353 0.67 LMNA (0.39) POLBLMNARAB9ACYP2C19KMT2A
SCHEMBL1832588 0.67 LMNA (0.35) POLBLMNARAB9ACYP2C19KMT2A
SCHEMBL31119397 0.67 LMNA (0.35) POLBLMNARAB9ACYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114981276-B Heterocyclic compound and harmful arthropod control composition containing same 住友化学株式会社 2024-09-27 CN disclosed
CN-116828982-A Method for treating rice seeds with improved agrochemical, micronutrient and colorant retention 法国特种经营公司 2023-09-29 CN disclosed
CN-116669552-A Agrochemical compositions with improved drift, spreadability and absorbency 拜耳公司 2023-08-29 CN disclosed
CN-116669550-A Agrochemical compositions with improved drift, spreading and rain-resistant properties 拜耳公司 2023-08-29 CN disclosed
CN-116669549-A Agrochemical compositions with improved drift, spreading, absorption and rain-resistant properties 拜耳公司 2023-08-29 CN disclosed
CN-116157397-A Heterocyclylpyridines as novel fungicides 拜耳公司 2023-05-23 CN disclosed
CN-116057056-A Azabicyclo-substituted heterocyclic compounds as fungicides 拜耳公司 2023-05-02 CN disclosed
US-20230115523-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION INCLUDING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-04-13 US disclosed
EP-4089096-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION INCLUDING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-11-16 EP disclosed
CN-114981276-A Heterocyclic compound and harmful arthropod control composition containing same 住友化学株式会社 2022-08-30 CN disclosed
WO-1999026944-A1 NEW COMPOUNDS WHICH ARE P2-PURINOCEPTOR 7-TRANSMEMBRANE (TM) G-PROTEIN COUPLED RECEPTOR ANTAGONISTS ASTRAZENEKA UK LIMITED (GB) 1999-06-03 WO disclosed
US-5500407-A Triazolopyrimidine herbicides CIBA-GEIGY CORPORATION (US) 1996-03-19 US disclosed
EP-0642512-A1 TRIAZOLOPYRIMIDINE HERBICIDES CIBA-GEIGY AG (CH) 1995-03-15 EP disclosed
WO-1994021640-A1 TRIAZOLOPYRIMIDINE HERBICIDES CIBA-GEIGY AG (CH) 1994-09-29 WO disclosed
EP-0353902-B1 SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-05 EP disclosed
US-5127936-A Substituted phenyltriazolopyrimidine herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-07-07 US disclosed
WO-1990012012-A1 SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-18 WO disclosed
CN-1040197-A SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES DU PONT (US) 1990-03-07 CN disclosed
EP-0353902-A1 Substituted phenyltriazolopyrimidine herbicides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-02-07 EP disclosed
EP-0114128-A1 3-Amino-2-oxo-azetidine derivatives containing in position 1 a nitrogen heterocyclic radical, process for their preparation, their use as therapeutical agents and intermediates for their preparation ROUSSEL-UCLAF (FR) 1984-07-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230115523-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION INCLUDING SAME C3AR1, C1S, C5 POLB 2949/4885LMNA 1171/4885RAB9A 642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.