Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 9/20 | 0.43 |
| ▸ | RAB9A | P51151 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099211 | 0.79 | ALDH1A1 (0.48) | MAPK1HPGDNPC1RAB9AKMT2A | |
| SCHEMBL9096830 | 0.79 | ALDH1A1 (0.48) | HPGDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16259088 | 0.74 | HPGD (0.64) | MAPK1HPGDPCSK9NPC1RAB9A | |
| SCHEMBL9098124 | 0.73 | HDAC3 (0.55) | MAPK1HPGDPCSK9NPC1RAB9A | |
| SCHEMBL9098108 | 0.73 | HDAC3 (0.55) | MAPK1HPGDPCSK9NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8906707 | 0.71 | HPGD (0.59) | MAPK1HPGDPCSK9NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8906703 | 0.71 | HPGD (0.59) | MAPK1HPGDPCSK9NPC1RAB9A | |
| SCHEMBL3463391 | 0.69 | MAPK1 (0.51) | MAPK1HPGDPCSK9NPC1RAB9A | |
| SCHEMBL1435770 | 0.68 | IDO1 (0.57) | MAPK1HPGDNPC1RAB9AKMT2A | |
| SCHEMBL1913774 | 0.67 | NPC1 (0.61) | MAPK1HPGDNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484774-A | 2, N6 -disubstituted adenosines, tri-O-ester derivatives and their pharmaceutical compositions to treat ischemias | NOVO NORDISK A/S (DK) | 1996-01-16 | — | — | US | disclosed |