Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098113 | 0.79 | MAPK1 (0.47) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9099211 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL12344738 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL12344745 | 0.74 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL29023732 | 0.74 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL9096833 | 0.72 | ALOX15 (0.47) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL9096824 | 0.72 | ALOX15 (0.47) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL30149949 | 0.70 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL3595617 | 0.70 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL31635992 | 0.69 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484774-A | 2, N6 -disubstituted adenosines, tri-O-ester derivatives and their pharmaceutical compositions to treat ischemias | NOVO NORDISK A/S (DK) | 1996-01-16 | — | — | US | disclosed |