Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | APEX1 | P27695 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098113 | 0.79 | MAPK1 (0.47) | ALDH1A1HPGDCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL9096830 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HPGDAPEX1L3MBTL1MAPT | |
| SCHEMBL29023733 | 0.76 | CYP1A2 (0.58) | ALDH1A1HPGDAPEX1CYP1A2CYP2D6 | |
| SCHEMBL10989220 | 0.73 | CYP1A2 (0.67) | ALDH1A1HPGDAPEX1CYP1A2CYP2D6 | |
| SCHEMBL29023728 | 0.72 | CYP1A2 (0.56) | ALDH1A1HPGDAPEX1CYP1A2CYP2D6 | |
| SCHEMBL3022326 | 0.71 | CYP1A2 (0.63) | ALDH1A1HPGDAPEX1CYP1A2CYP2D6 | |
| SCHEMBL3026942 | 0.71 | CYP1A2 (0.63) | ALDH1A1HPGDAPEX1CYP1A2CYP2D6 | |
| SCHEMBL10037466 | 0.71 | APEX1 (0.64) | ALDH1A1HPGDAPEX1CYP1A2CYP2D6 | |
| SCHEMBL3026939 | 0.71 | CYP1A2 (0.63) | ALDH1A1HPGDAPEX1CYP1A2CYP2D6 | |
| SCHEMBL3022330 | 0.71 | CYP1A2 (0.63) | ALDH1A1HPGDAPEX1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484774-A | 2, N6 -disubstituted adenosines, tri-O-ester derivatives and their pharmaceutical compositions to treat ischemias | NOVO NORDISK A/S (DK) | 1996-01-16 | — | — | US | disclosed |