Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.47 |
| ▸ | TK1 | P04183 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098312 | 1.00 | TYMS (0.53) | TYMSLMNASMN1; SMN2RNASE1TK1 | |
| SCHEMBL8327674 | 0.91 | LMNA (0.48) | TYMSLMNASMN1; SMN2RNASE1TK1 | |
| SCHEMBL8327670 | 0.91 | LMNA (0.48) | TYMSLMNASMN1; SMN2RNASE1TK1 | |
| SCHEMBL9096639 | 0.90 | TYMS (0.51) | TYMSLMNASMN1; SMN2RNASE1TK1 | |
| SCHEMBL9096644 | 0.90 | TYMS (0.51) | TYMSLMNASMN1; SMN2RNASE1TK1 | |
| SCHEMBL9098753 | 0.90 | RNASE1 (0.53) | TYMSLMNASMN1; SMN2RNASE1TK1 | |
| SCHEMBL9098615 | 0.90 | TYMS (0.50) | TYMSLMNASMN1; SMN2RNASE1TK1 | |
| SCHEMBL9098612 | 0.90 | TYMS (0.50) | TYMSLMNASMN1; SMN2RNASE1TK1 | |
| SCHEMBL9098751 | 0.90 | RNASE1 (0.53) | TYMSLMNASMN1; SMN2RNASE1TK1 | |
| SCHEMBL8323429 | 0.90 | TYMS (0.47) | TYMSLMNASMN1; SMN2RNASE1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155113-A | Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | claimed |
| EP-0180188-B1 | A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | claimed |
| EP-0323441-B1 | 5-Fluorouracil derivatives | OTSUKA PHARMA CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5155113-A | Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0180188-B1 | A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |
| US-4983609-A | Anticancer agents | OTSUKA PHARMACEUTICAL (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4864021-A | ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0323441-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0180897-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |