Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28257509 | 0.83 | ESR1 (0.50) | ESR1ESR2HPGDHSD17B10KDM4E | |
| SCHEMBL9507456 | 0.77 | ESR1 (0.51) | ESR1ESR2HPGDHSD17B10KDM4E | |
| SCHEMBL1810392 | 0.77 | ESR1 (0.59) | ESR1ESR2HPGDHSD17B10KDM4E | |
| SCHEMBL9067488 | 0.75 | ESR1 (0.76) | ESR1ESR2HPGDHSD17B10KDM4E | |
| SCHEMBL501719 | 0.74 | ESR1 (0.50) | ESR1ESR2HPGDHSD17B10KDM4E | |
| SCHEMBL29357094 | 0.74 | ALDH1A1 (0.65) | ESR1ESR2HPGDHSD17B10KDM4E | |
| Benzene SCHEMBL27738764 | 0.74 | KMT2A (0.55) | ESR1ESR2HPGDHSD17B10KDM4E | |
| SCHEMBL56188 | 0.74 | ALDH1A1 (0.65) | ESR1ESR2HPGDHSD17B10KDM4E | |
| SCHEMBL9673098 | 0.74 | G6PD (0.46) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL14490114 | 0.74 | KMT2A (0.61) | ESR1ESR2KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |