Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17614153 | 1.00 | AHR (0.49) | AHRKMT2AMEN1KDM4EMAPT | |
| SCHEMBL22302361 | 0.95 | LMNA (0.42) | AHRKMT2AMEN1KDM4EMAPT | |
| SCHEMBL21019564 | 0.92 | AHR (0.41) | AHRKMT2AMEN1KDM4EMAPT | |
| SCHEMBL24470239 | 0.90 | MAPT (0.49) | AHRKMT2AMEN1KDM4EMAPT | |
| SCHEMBL21123027 | 0.89 | AHR (0.42) | AHRKMT2AMEN1KDM4EMAPT | |
| SCHEMBL21122829 | 0.89 | MAOA (0.38) | AHRKMT2AMEN1KDM4EMAPT | |
| SCHEMBL30592720 | 0.89 | AHR (0.45) | AHRKMT2AMEN1KDM4EMAPT | |
| SCHEMBL20249846 | 0.85 | MAOB (0.47) | AHRKMT2AMEN1KDM4EMAPT | |
| SCHEMBL16440658 | 0.84 | PLA2G2A (0.48) | AHRKMT2AMEN1KDM4EMAPT | |
| SCHEMBL21123212 | 0.84 | MEN1 (0.44) | AHRKMT2AMEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510503-A | Bisphosphines for asymmetric hydrogenation catalysts | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |