Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099219 | 1.00 | ALDH1A1 (0.54) | ALDH1A1HPGDALOX5MAPTLMNA | |
| SCHEMBL24214328 | 0.82 | HTT (0.53) | ALDH1A1HPGDALOX5MAPTLMNA | |
| SCHEMBL25955151 | 0.81 | HDAC3 (0.49) | ALDH1A1HPGDMAPTSMN1; SMN2RECQL | |
| SCHEMBL9098124 | 0.79 | HDAC3 (0.55) | ALDH1A1HPGDMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9098108 | 0.79 | HDAC3 (0.55) | ALDH1A1HPGDMAPTSMN1; SMN2NPC1 | |
| SCHEMBL19385934 | 0.77 | HPGD (0.69) | ALDH1A1HPGDALOX5MAPTLMNA | |
| SCHEMBL9096833 | 0.77 | ALOX15 (0.47) | ALDH1A1ALOX5MAPTLMNASMN1; SMN2 | |
| SCHEMBL9096824 | 0.77 | ALOX15 (0.47) | ALDH1A1ALOX5MAPTLMNASMN1; SMN2 | |
| SCHEMBL13212017 | 0.77 | CYP1A2 (0.64) | ALDH1A1HPGDALOX5MAPTLMNA | |
| SCHEMBL9404273 | 0.76 | MTNR1A (0.64) | ALDH1A1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484774-A | 2, N6 -disubstituted adenosines, tri-O-ester derivatives and their pharmaceutical compositions to treat ischemias | NOVO NORDISK A/S (DK) | 1996-01-16 | — | — | US | disclosed |