SCHEMBL9099313

SCHEMBL9099313

Cc1c(-c2ccccc2F)n[nH]c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.47
HTR7 P34969 2/20 0.44
MAPT P10636 2/20 0.43
HPGD P15428 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
POLB P06746 1/20 0.43
CASP3 P42574 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
DCUN1D1 Q96GG9 1/20 0.42
MBNL1 Q9NR56 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
MAP4K1 Q92918 2/20 0.39
NOTUM Q6P988 1/20 0.39
IDO1 P14902 1/20 0.39
KDM4E B2RXH2 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
PIM1 P11309 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9099297 0.80 MAPT (0.43) HSP90AA1MAPTHPGDSMN1; SMN2POLB
SCHEMBL31468297 0.79 HTR7 (0.44) HSP90AA1HTR7MAPTHPGDSMN1; SMN2
SCHEMBL1701438 0.79 HTR7 (0.41) HSP90AA1HTR7MAPTHPGDSMN1; SMN2
SCHEMBL9278955 0.73 TDP1 (0.40) HSP90AA1HTR7POLBDCUN1D1MBNL1
SCHEMBL397005 0.69 IDO1 (0.46) HSP90AA1HTR7MAPTHPGDSMN1; SMN2
SCHEMBL27511626 0.68 HSP90AA1 (0.49) HSP90AA1HTR7MAPTSMN1; SMN2KDM4E
SCHEMBL11269697 0.68 HSP90AA1 (0.56) HSP90AA1MAPTSMN1; SMN2MAP4K1PIM1
SCHEMBL11625109 0.68 MBNL1 (0.47) HSP90AA1HTR7MAPTSMN1; SMN2DCUN1D1
SCHEMBL28177130 0.68 IDO1 (0.58) HTR7HPGDDCUN1D1MAP4K1IDO1
SCHEMBL17290482 0.68 MBNL1 (0.41) MAPTHPGDSMN1; SMN2MBNL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996015116-A1 HERBICIDAL PYRAZOLES ZENECA LIMITED (GB) 1996-05-23 WO disclosed