Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796993 | 0.77 | TSHR (0.56) | LMNAMEN1KMT2ATHRBBLM | |
| SCHEMBL2222781 | 0.77 | NPC1 (0.51) | LMNAMEN1KMT2ATHRBBLM | |
| SCHEMBL17005576 | 0.73 | TSHR (0.55) | LMNAMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL6199923 | 0.72 | LMNA (0.48) | LMNAMEN1KMT2ATHRBBLM | |
| SCHEMBL14039520 | 0.72 | ALDH1A1 (0.46) | LMNAKMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL1092957 | 0.72 | SCN1A (0.44) | LMNAMEN1KMT2ATHRBBLM | |
| SCHEMBL6304130 | 0.72 | HCAR2 (0.50) | LMNAMEN1KMT2ATHRBBLM | |
| SCHEMBL733572 | 0.72 | MAPT (0.57) | KMT2ASMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL30635255 | 0.71 | LMNA (0.57) | LMNAMEN1KMT2ATHRBBLM | |
| SCHEMBL121356 | 0.71 | LMNA (0.57) | LMNAMEN1KMT2ATHRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489714-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1996-02-06 | — | — | US | claimed |
| US-5449834-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1995-09-12 | — | — | US | claimed |
| US-5489714-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5489714-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5449834-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1995-09-12 | — | — | US | disclosed |
| US-5449834-A | Method of synthesizing 2,6-dinitro benzyl compounds | PPG INDUSTRIES, INC. (US) | 1995-09-12 | — | — | US | disclosed |