Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2222781 | 0.82 | NPC1 (0.51) | TSHRTP53LMNAKMT2AMEN1 | |
| SCHEMBL6304130 | 0.80 | HCAR2 (0.50) | TSHRTP53LMNAKMT2AMEN1 | |
| Benzene SCHEMBL28217563 | 0.78 | TSHR (0.55) | TSHRLMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL11395358 | 0.78 | LMNA (0.44) | TSHRLMNAKMT2AMEN1THRB | |
| SCHEMBL6199923 | 0.77 | LMNA (0.48) | TSHRLMNAKMT2AMEN1THRB | |
| SCHEMBL14039520 | 0.77 | ALDH1A1 (0.46) | TSHRLMNAKMT2AGAAALDH1A1 | |
| SCHEMBL9099494 | 0.77 | LMNA (0.41) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL1092957 | 0.77 | SCN1A (0.44) | TSHRLMNAKMT2AMEN1THRB | |
| SCHEMBL3545045 | 0.76 | TP53 (0.58) | TSHRTP53LMNAKMT2ARECQL | |
| SCHEMBL4179476 | 0.76 | TSHR (0.58) | TSHRTP53LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040039206-A1 | Process for resolving racemic mixtures of piperidine derivatives | MOHER ERIC DAVID (US) | 2004-02-26 | — | — | US | disclosed |
| EP-1341762-A1 | PROCESS FOR RESOLVING RACEMIC MIXTURES OF PIPERIDINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002068391-A1 | PROCESS FOR RESOLVING RACEMIC MIXTURES OF PIPERIDINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039206-A1 | Process for resolving racemic mixtures of piperidine derivatives | SRR, OPRM1, SRM | TSHR 2004/4885TP53 4127/4885LMNA 1605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.