SCHEMBL9099580

SCHEMBL9099580

Cc1ccc(S(=O)(=O)O)cc1C1CCC(C(C)(C)C)CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SCN9A Q15858 1/20 0.37
HSD11B1 P28845 1/20 0.35
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA12 O43570 2/20 0.35
CA7 P43166 2/20 0.35
CA14 Q9ULX7 2/20 0.35
GAA P10253 2/20 0.34
MAPT P10636 2/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.33
HTT P42858 1/20 0.33
GPR119 Q8TDV5 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29104732 0.89 CA1 (0.41) ALDH1A1CA1CA2CA12CA7
SCHEMBL8763566 0.83 ALDH1A1 (0.43) ALDH1A1CA1CA2CA12CA7
SCHEMBL778058 0.82 CA1 (0.36) ALDH1A1HSD11B1CA1CA2CA12
SCHEMBL656155 0.82 PTGS2 (0.42) ALDH1A1SMN1; SMN2CA1CA2CA12
SCHEMBL8788235 0.80 CYP2D6 (0.37) ALDH1A1HSD11B1CA1CA2CA12
SCHEMBL8089603 0.78 MEN1 (0.38) ALDH1A1SMN1; SMN2SCN9ACA1CA2
SCHEMBL6942861 0.77 JAK2 (0.44) CA1CA2CA12CA7CA14
SCHEMBL9099567 0.75 SCN9A (0.38) ALDH1A1SCN9AHSD11B1GAAMAPT
SCHEMBL27009904 0.75 CHRM5 (0.37) ALDH1A1GAAMAPTLMNATP53
SCHEMBL2486113 0.74 TSHR (0.35) ALDH1A1SMN1; SMN2CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489501-A MIXTURES OF TWO COORDINATION COMPOUNDS WHICH REACT TO FORM NEW COORDINATION COMPOUND WHILE CAUSING VISIBLE COLOR CHANGES RICOH COMPANY, LTD. (JP) 1996-02-06 US disclosed
US-5446011-A Imagewise coloring when heating; mixture of n-substituted indole, aromatic polyhydroxy compound, carbonyl compound and an acid RICOH COMPANY, LTD. (JP) 1995-08-29 US disclosed