Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099659 | 1.00 | FFAR3 (0.38) | FFAR3LDHASRRMCL1 | |
| SCHEMBL5857009 | 0.86 | LDHA (0.40) | LDHASRR | |
| SCHEMBL9097305 | 0.83 | HDAC3 (0.41) | FFAR3LDHASRR | |
| SCHEMBL9097309 | 0.83 | HDAC3 (0.41) | FFAR3LDHASRR | |
| SCHEMBL12593429 | 0.79 | MGAM (0.38) | — | |
| SCHEMBL7596544 | 0.78 | — | — | |
| SCHEMBL1763000 | 0.77 | GAA (0.47) | — | |
| SCHEMBL9408203 | 0.76 | GAA (0.50) | — | |
| SCHEMBL9408202 | 0.76 | GAA (0.50) | — | |
| SCHEMBL868459 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609371-B1 | THIENOPYRAZINE-2,3-DIONES USEFUL FOR TREATING CNS DISORDERS, AND THEIR PREPARATION. | NOVO NORDISK AS (DK) | 1996-04-24 | — | — | EP | disclosed |
| EP-0609371-A1 | THIENOPYRAZINE-2,3-DIONES AND THEIR PREPARATION AND USE. | NOVO NORDISK AS (DK) | 1994-08-10 | — | — | EP | disclosed |
| US-5284847-A | Neurological and psychological disorders; antagonist at the glycine binding site on the N-methyl-D-aspartate receptor complex | NOVO NORDISK A/S (DK) | 1994-02-08 | — | — | US | disclosed |
| WO-1993008197-A1 | THIENOPYRAZINE-2,3-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-04-29 | — | — | WO | disclosed |