Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | APC | P25054 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099746 | 1.00 | OPRD1 (0.53) | OPRD1OPRM1OPRK1APCCTSL | |
| SCHEMBL9153129 | 0.95 | CTSL (0.55) | CTSLCTSBCTSSCTSKPTPN1 | |
| SCHEMBL6371492 | 0.95 | CTSL (0.55) | CTSLCTSBCTSSCTSKPTPN1 | |
| SCHEMBL6372162 | 0.91 | CTSL (0.62) | APCCTSLCTSBCTSSCTSK | |
| SCHEMBL13588070 | 0.91 | MME (0.56) | OPRD1OPRM1OPRK1CTSLCTSB | |
| SCHEMBL19065177 | 0.91 | MME (0.56) | OPRD1OPRM1OPRK1CTSLCTSB | |
| SCHEMBL28902023 | 0.88 | MDM4 (0.61) | OPRD1OPRM1OPRK1CTSLCTSB | |
| SCHEMBL9333779 | 0.88 | MME (0.54) | OPRD1OPRM1OPRK1CTSLCTSB | |
| SCHEMBL13588071 | 0.88 | MDM4 (0.61) | OPRD1OPRM1OPRK1CTSLCTSB | |
| SCHEMBL10948828 | 0.86 | TACR1 (0.51) | OPRD1OPRM1OPRK1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456138-B1 | Peptide-amidase and its application | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 1996-03-13 | — | — | EP | disclosed |
| US-5369016-A | Catalytic hydrolysis of peptides to form acids | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 1994-11-29 | — | — | US | disclosed |
| US-5190875-A | PEPTIDE AMIDASE AND THE USE THEREOF | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0456138-A2 | Peptide-amidase and its application | FORSCHUNGSZENTRUM JÜLICH GMBH (DE) | 1991-11-13 | — | — | EP | disclosed |