Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | F7 | P08709 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.32 |
| ▸ | PLAU | P00749 | 2/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.31 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103604 | 0.83 | F10 (0.41) | F2F10F7PRSS1PLAU | |
| SCHEMBL9101801 | 0.80 | F10 (0.47) | F2F10F7PRSS1PLAU | |
| SCHEMBL548437 | 0.70 | F10 (0.49) | F2F10F7PRSS1PLAU | |
| SCHEMBL5329388 | 0.70 | F10 (0.49) | F2F10F7PRSS1PLAU | |
| SCHEMBL6753172 | 0.66 | F2 (0.48) | F2F10F7PRSS1PLAU | |
| SCHEMBL7879342 | 0.64 | PLAU (0.65) | F2F10F7PRSS1PLAU | |
| Hydrochloric Acid SCHEMBL11298806 | 0.64 | PLAU (0.65) | F2F10F7PRSS1PLAU | |
| SCHEMBL28476316 | 0.63 | MAPKAPK2 (0.45) | F2 | |
| SCHEMBL6879892 | 0.63 | NISCH (0.42) | F2F10F7 | |
| SCHEMBL23775704 | 0.62 | PLAU (0.59) | F2F10F7PRSS1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739202-A1 | USE OF BIS(AMIDINOBENZIMIDAZOLES) IN THE MANUFACTURE OF MEDICAMENT FOR INHIBITING RETROVIRAL INTEGRASE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-10-30 | — | — | EP | disclosed |
| WO-1995019772-A1 | USE OF BIS(AMIDINOBENZIMIDAZOLES) IN THE MANUFACTURE OF MEDICAMENT FOR INHIBITING RETROVIRAL INTEGRASE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1995-07-27 | — | — | WO | disclosed |