Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100901 | 0.83 | F2 (0.33) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL27659971 | 0.80 | F10 (0.60) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL27639305 | 0.71 | F10 (0.57) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL27659973 | 0.71 | F10 (0.78) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL548419 | 0.70 | F10 (0.63) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL65730 | 0.70 | F10 (0.77) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL6880765 | 0.70 | F10 (0.54) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL4322200 | 0.69 | TPSAB1 (0.78) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL9043744 | 0.69 | TOP2A (0.48) | F10 | |
| SCHEMBL548407 | 0.68 | F10 (0.60) | F10TPSAB1PRSS1F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739202-A1 | USE OF BIS(AMIDINOBENZIMIDAZOLES) IN THE MANUFACTURE OF MEDICAMENT FOR INHIBITING RETROVIRAL INTEGRASE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-10-30 | — | — | EP | disclosed |
| WO-1995019772-A1 | USE OF BIS(AMIDINOBENZIMIDAZOLES) IN THE MANUFACTURE OF MEDICAMENT FOR INHIBITING RETROVIRAL INTEGRASE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1995-07-27 | — | — | WO | disclosed |