Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 4/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880765 | 0.84 | F10 (0.54) | F10F2F7 | |
| SCHEMBL9023171 | 0.82 | F10 (0.48) | F10F2F7 | |
| SCHEMBL6879930 | 0.82 | PRMT1 (0.41) | NISCHF10PRMT1FDPS | |
| SCHEMBL4314492 | 0.70 | F10 (0.48) | F10F2F7 | |
| SCHEMBL14854582 | 0.69 | PRMT1 (0.49) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL13204584 | 0.69 | NISCH (0.54) | NISCHPRMT1 | |
| SCHEMBL9029139 | 0.69 | NISCH (0.54) | NISCHPRMT1 | |
| SCHEMBL4316759 | 0.69 | TPSAB1 (0.48) | F10F2F7 | |
| SCHEMBL9113676 | 0.68 | NISCH (0.52) | NISCHPRMT1 | |
| SCHEMBL548359 | 0.68 | NISCH (0.52) | NISCHPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815461-B1 | ADMINISTERING BIS-BENZIMIDAZOLE COMPOUND; TREATING HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTION | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2004-11-09 | — | — | US | disclosed |
| EP-0739202-B1 | USE OF BIS(AMIDINOBENZIMIDAZOLES) IN THE MANUFACTURE OF MEDICAMENT FOR INHIBITING RETROVIRAL INTEGRASE | UNIV NORTH CAROLINA (US) | 1998-12-16 | — | — | EP | disclosed |