Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9102868 | 0.87 | TSHR (0.40) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL5064327 | 0.84 | ABCB1 (0.47) | G6PDCRHBPCRHR2 | |
| SCHEMBL17416629 | 0.80 | CTSD (0.43) | LMNAKDM4EHPGDNPC1RAB9A | |
| SCHEMBL27356523 | 0.79 | KDM4E (0.39) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL5053857 | 0.77 | ABCB1 (0.49) | G6PDCRHBPCRHR2 | |
| SCHEMBL2482845 | 0.77 | ABCB1 (0.51) | CYP3A4NPC1RAB9A | |
| SCHEMBL18091874 | 0.77 | MAPT (0.43) | MAPTHTTLMNAKDM4EMEN1 | |
| SCHEMBL18091865 | 0.76 | NPC1 (0.48) | MAPTALDH1A1L3MBTL1HTTLMNA | |
| SCHEMBL9100311 | 0.76 | RAB9A (0.43) | MAPTLMNAPKMNPC1RAB9A | |
| SCHEMBL18091870 | 0.75 | NPC1 (0.35) | MAPTLMNAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |