Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | METAP2 | P50579 | 1/20 | 0.61 |
| ▸ | METAP1 | P53582 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28459061 | 0.90 | LMNA (0.69) | L3MBTL1LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL250301 | 0.83 | LMNA (0.65) | L3MBTL1LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL27890151 | 0.83 | LMNA (0.57) | L3MBTL1LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL795857 | 0.83 | HSP90AA1 (0.68) | L3MBTL1LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL10385035 | 0.83 | LMNA (0.72) | L3MBTL1LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL10750474 | 0.83 | LMNA (0.63) | L3MBTL1LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL10752189 | 0.83 | LMNA (0.60) | L3MBTL1LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL4457246 | 0.82 | LMNA (0.66) | L3MBTL1LMNAMETAP2METAP1HDAC6 | |
| Hydrochloric Acid SCHEMBL2563239 | 0.82 | LMNA (0.63) | L3MBTL1LMNAMETAP2METAP1HDAC6 | |
| Butanedione SCHEMBL5530736 | 0.82 | LMNA (0.63) | L3MBTL1LMNAMETAP2METAP1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124455-A | Enzyme inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-23 | — | — | US | claimed |
| EP-0470805-B1 | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents | AMERICAN HOME PROD (US) | 1994-09-07 | — | — | EP | disclosed |
| US-5124455-A | Enzyme inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |
| EP-0470805-A1 | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-02-12 | — | — | EP | disclosed |
| EP-0208281-B1 | QUINOLINE 8-CARBOXYLIC-ACID AZOLIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1991-01-30 | — | — | EP | disclosed |
| EP-0208281-A2 | Quinoline 8-carboxylic-acid azolides, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1987-01-14 | — | — | EP | disclosed |