SCHEMBL9100065

SCHEMBL9100065

CCCS(=O)(=O)ON1c2ccccc2Sc2cccc(-c3nccc(C)n3)c21

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BCHE P06276 4/20 0.33
TGFBR1 P36897 1/20 0.32
MAPT P10636 2/20 0.31
HTT P42858 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
PABPC1 P11940 1/20 0.30
APOBEC3A P31941 1/20 0.30
EIF4H Q15056 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9101866 0.90 BCHE (0.33) BCHEMAPTHTTPOLB
SCHEMBL9102549 0.90 MAPT (0.31) BCHEMAPTHTT
SCHEMBL9105126 0.90 HPGD (0.31) BCHEMAPTHTT
SCHEMBL9101269 0.89 BCHE (0.32) BCHEMAPTHTTPOLB
SCHEMBL9104286 0.87 BCHE (0.34) BCHEMAPTPOLB
SCHEMBL9105492 0.85 BCHE (0.34) BCHETGFBR1MAPTHTT
SCHEMBL9101839 0.83 TGFBR1 (0.31) TGFBR1RXFP1
SCHEMBL9104590 0.83 BCHE (0.33) BCHE
SCHEMBL9104005 0.82 BCHE (0.35) BCHEMAPTHTT
SCHEMBL9104104 0.80 THRB (0.36) BCHEMAPTHTTRXFP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed