Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.41 |
| ▸ | WNT3A | P56704 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053811 | 0.83 | ABCB1 (0.50) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7130710 | 0.81 | NPC1 (0.38) | MAPTNPC1RAB9ACTNNB1WNT3A | |
| SCHEMBL9101948 | 0.80 | NPC1 (0.38) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18091858 | 0.78 | CTNNB1 (0.58) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9102323 | 0.77 | NPC1 (0.38) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9236827 | 0.77 | CTNNB1 (0.48) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17416603 | 0.74 | RAB9A (0.36) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18091872 | 0.73 | ABCB1 (0.43) | — | |
| SCHEMBL5057237 | 0.73 | NPC1 (0.46) | TP53MAPTNPC1RAB9ATSHR | |
| SCHEMBL8875639 | 0.72 | CTNNB1 (0.35) | MAPTNPC1RAB9ACTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |