Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101948 | 0.85 | NPC1 (0.38) | NPC1RAB9AALDH1A1MAPTCTNNB1 | |
| SCHEMBL5705240 | 0.84 | NPC1 (0.39) | NPC1RAB9AALDH1A1MAPTCYP3A4 | |
| SCHEMBL9102323 | 0.82 | NPC1 (0.38) | NPC1RAB9AALDH1A1MAPTCYP3A4 | |
| SCHEMBL9101301 | 0.81 | TP53 (0.43) | NPC1RAB9AALDH1A1MAPTCTNNB1 | |
| Chromafenozide SCHEMBL73335 | 0.80 | ABCB1 (0.56) | ABCB1CYP3A4CYP2C19HTTCYP2C9 | |
| SCHEMBL7121475 | 0.80 | ABCB1 (0.48) | ABCB1CYP3A4 | |
| SCHEMBL7474498 | 0.78 | NPC1 (0.33) | NPC1RAB9AALDH1A1MAPTABCB1 | |
| SCHEMBL682224 | 0.77 | RAB9A (0.46) | NPC1RAB9AALDH1A1MAPTCTNNB1 | |
| SCHEMBL9253142 | 0.77 | NPC1 (0.34) | NPC1RAB9AALDH1A1MAPTABCB1 | |
| SCHEMBL16239577 | 0.76 | ABCB1 (0.33) | RAB9AABCB1CYP3A4CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |
| JP-2003063908-A | OGAWA (INVENTOR'S NAME) TYPE PESTICIDE PREPARATION | NIPPON KAYAKU CO LTD | 2003-03-05 | — | — | JP | disclosed |