Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101948 | 0.85 | NPC1 (0.38) | NPC1RAB9AALDH1A1MAPTHTT | |
| SCHEMBL5057233 | 0.84 | ABCB1 (0.42) | NPC1RAB9AALDH1A1MAPTHTT | |
| SCHEMBL7130710 | 0.82 | NPC1 (0.38) | NPC1RAB9AALDH1A1MAPTHTT | |
| SCHEMBL9101301 | 0.77 | TP53 (0.43) | NPC1RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL27500902 | 0.71 | TSHR (0.42) | NPC1RAB9AALDH1A1MAPTHTT | |
| SCHEMBL5057116 | 0.70 | ABCB1 (0.42) | NPC1RAB9AALDH1A1MAPTHTT | |
| SCHEMBL8875639 | 0.69 | CTNNB1 (0.35) | NPC1RAB9AALDH1A1MAPTHTT | |
| SCHEMBL5056865 | 0.69 | ABCB1 (0.45) | NPC1RAB9A | |
| SCHEMBL7121475 | 0.67 | ABCB1 (0.48) | CYP3A4 | |
| SCHEMBL7041343 | 0.67 | MTNR1A (0.36) | NPC1RAB9AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |