SCHEMBL910131

SCHEMBL910131

CC(C)OC(=O)C(=O)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
ADRA1A P35348 1/20 0.43
PDE4D Q08499 1/20 0.43
CA12 O43570 9/20 0.39
CA1 P00915 9/20 0.39
CA2 P00918 9/20 0.39
CA9 Q16790 9/20 0.39
CA7 P43166 7/20 0.39
CA14 Q9ULX7 7/20 0.39
HCAR2 Q8TDS4 1/20 0.39
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 3/20 0.34
AKR1B10 O60218 1/20 0.33
AKR1B1 P15121 1/20 0.33
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PDCD1 Q15116 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5705632 0.89 TSHR (0.42) TSHRADRA1APDE4DCA12CA1
SCHEMBL297916 0.83 TSHR (0.59) TSHRADRA1APDE4DCA12CA1
SCHEMBL27926059 0.80 TSHR (0.56) TSHRADRA1APDE4DCA12CA1
SCHEMBL29220140 0.79 TSHR (0.48) TSHRADRA1APDE4DCA12CA1
SCHEMBL21194066 0.78 TSHR (0.36) TSHRCA12CA1CA2CA9
SCHEMBL11510451 0.78 TSHR (0.53) TSHRADRA1APDE4DCA12CA1
SCHEMBL16048299 0.78 TSHR (0.53) TSHRADRA1APDE4DCA12CA1
SCHEMBL20565358 0.78 TSHR (0.53) TSHRADRA1APDE4DCA12CA1
SCHEMBL1462514 0.78 TSHR (0.38) TSHRADRA1APDE4DALDH1A1
SCHEMBL1088971 0.76 TSHR (0.40) TSHRADRA1APDE4DCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9487602-B2 Furan based resin, process for the preparation thereof, and use of the compound DSM IP ASSETS B.V. (NL) 2016-11-08 US claimed
US-20130109822-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2013-05-02 US claimed
US-20110306735-A1 PROCESS FOR THE PREPARATION OF A HYDROXY-AROMATIC RESIN; HYDROXY-AROMATIC RESIN, AND MODIFICATION THEREOF DSM IP ASSETS B.V. (NL) 2011-12-15 US claimed
US-20110021740-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2011-01-27 US claimed
EP-2222656-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP Assets B.V. (NL) 2010-09-01 EP claimed
US-20090203851-A1 Process for the Preparation of a Hydroxy-Aromatic Resin: Hydroxy-Aromatic Resin, and Modification Thereof DSM IP ASSETS B.V. (NL) 2009-08-13 US claimed
WO-2009077587-A1 FURAN BASED RESIN, PROCESS FOR THE PREPARATION THEREOF, AND USE OF THE COMPOUND DSM IP ASSETS B.V. (NL) 2009-06-25 WO claimed
EP-2024317-A2 PROCESS FOR THE PREPARATION OF A HYDROXY-AROMATIC RESIN; HYDROXY-AROMATIC RESIN, AND MODIFICATION THEREOF DSMIP Assets B.V. (NL) 2009-02-18 EP claimed
WO-2007140941-A2 PROCESS FOR THE PREPARATION OF A HYDROXY-AROMATIC RESIN; HYDROXY-AROMATIC RESIN, AND MODIFICATION THEREOF DSM IP ASSETS B.V. (NL) 2007-12-13 WO claimed
US-11771715-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-10-03 US disclosed
US-11766449-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-09-26 US disclosed
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. 2023-07-20 US disclosed
US-11679120-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-06-20 US disclosed
US-9765022-B2 Disulfide compounds for delivery of pharmaceutical agents TUFTS UNIVERSITY (US) 2017-09-19 US disclosed
US-20050176916-A1 Nitrogen-containing compound, the preparation thereof and application in amino-aldehyde resins DSM I.P. ASSETS B.V. (NL) 2005-08-11 US disclosed
EP-1507770-A2 NITROGEN-CONTAINING COMPOUND, THE PREPARATION THEREOF AND APPLICATION IN AMINO-ALDEHYDE RESINS DSM IP Assets B.V. (NL) 2005-02-23 EP disclosed
WO-2004110614-A1 ENCAPSULATED MATERIALS DSM IP ASSETS B.V. (NL) 2004-12-23 WO disclosed
WO-2003101973-A2 NITROGEN-CONTAINING COMPOUND, THE PREPARATION THEREOF AND APPLICATION IN AMINO-ALDEHYDE RESINS DSM IP ASSETS B.V. (NL) 2003-12-11 WO disclosed
US-6348617-B1 REACTING PYRUVIC ACID COMPOUND IN WATER WITH AMMONIUM OR ALKALI METAL BISULFITE TO GIVE AQUEOUS SOLUTION OF BISULFITE ADDUCT, ISOLATING BY PHASE SEPARATION, OPTIONALLY USING HYDROPHOBIC SOLVENT, CONTACTING WITH ACID TO DECOMPOSE ADDUCT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-19 US disclosed
EP-0937703-A1 METHOD FOR PURIFYING PYRUVIC ACID COMPOUNDS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1999-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11771715-B2 Circular RNA compositions and methods RTCB, HNRNPA1, HNRNPAB TSHR 1491/4885ADRA1A 4812/4885PDE4D 3623/4885
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS RTCB, HNRNPA1, HNRNPAB TSHR 1491/4885ADRA1A 4812/4885PDE4D 3623/4885
US-11679120-B2 Circular RNA compositions and methods RTCB, HNRNPA1, HNRNPAB TSHR 1491/4885ADRA1A 4812/4885PDE4D 3623/4885
US-11766449-B2 Circular RNA compositions and methods RTCB, RNGTT, HNRNPAB TSHR 1390/4885ADRA1A 4793/4885PDE4D 3412/4885
US-20090203851-A1 Process for the Preparation of a Hydroxy-Aromatic Resin: Hydroxy-Aromatic Resin, and Modification Thereof HRH3, HRH1, C9 TSHR 3620/4885ADRA1A 94/4885PDE4D 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.