SCHEMBL9101466

SCHEMBL9101466

CCCCCCCC(C)(C(=O)O)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.50
LPAR1 Q92633 1/20 0.46
LPAR3 Q9UBY5 1/20 0.46
FAAH O00519 8/20 0.44
CES1 P23141 5/20 0.44
MEN1 O00255 1/20 0.44
CYP1A2 P05177 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
SLC22A6 Q4U2R8 1/20 0.40
SLC22A8 Q8TCC7 1/20 0.40
GPR84 Q9NQS5 1/20 0.40
PPARG P37231 1/20 0.40
PPARD Q03181 1/20 0.40
PPARA Q07869 1/20 0.40
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9098440 1.00 CES2 (0.50) CES2LPAR1LPAR3FAAHCES1
SCHEMBL9101764 0.98 CES2 (0.47) CES2LPAR1LPAR3FAAHCES1
SCHEMBL9100047 0.92 CES2 (0.39) CES2LPAR1LPAR3FAAHCES1
SCHEMBL11297852 0.92 CES2 (0.39) CES2LPAR1LPAR3FAAHCES1
SCHEMBL11301629 0.92 CES2 (0.39) CES2LPAR1LPAR3FAAHCES1
SCHEMBL9102150 0.83 CES2 (0.33) CES2FAAHCES1MEN1CYP1A2
SCHEMBL28729530 0.82 FDPS (0.44) CES2MEN1KMT2AHSD17B10ALDH1A1
SCHEMBL28727538 0.82 FDPS (0.44) CES2MEN1KMT2AHSD17B10ALDH1A1
SCHEMBL28729579 0.82 FDPS (0.44) CES2MEN1KMT2AHSD17B10ALDH1A1
SCHEMBL28727457 0.82 FDPS (0.44) CES2MEN1KMT2AHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460802-A1 TRIFLUOROMETHYLTHIOPHENIUM DERIVATIVE SALTS, PROCESS FOR PRODUCITON THEREOF, AND PROCESS FOR PRODUCTION OF TRIFLUOROMETHYL-CONTAINING COMPOUNDS USING SAME Nagoya Institute of Technology (JP) 2012-06-06 EP disclosed