Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | RORB | Q92753 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9104094 | 0.89 | THRB (0.38) | LMNAHDAC1HDAC6HDAC3FNTA | |
| SCHEMBL9103994 | 0.89 | LMNA (0.36) | LMNAHDAC1HDAC6HDAC3FNTA | |
| SCHEMBL9101400 | 0.89 | LMNA (0.36) | LMNAHDAC1HDAC6HDAC3FNTA | |
| SCHEMBL9102715 | 0.87 | HDAC6 (0.35) | LMNAHDAC1HDAC6HDAC3FNTA | |
| SCHEMBL9102277 | 0.85 | LMNA (0.34) | LMNAHDAC1HDAC6HDAC3FNTA | |
| SCHEMBL9100577 | 0.84 | HDAC1 (0.42) | HDAC1HDAC6BCHEMAPT | |
| SCHEMBL9102596 | 0.83 | MEN1 (0.33) | LMNAHDAC6HDAC3KMT2ALIMK1 | |
| SCHEMBL9099076 | 0.83 | RORB (0.35) | HDAC1HDAC6HDAC3BCHEKMT2A | |
| SCHEMBL9105569 | 0.80 | BCHE (0.33) | HDAC1HDAC6FNTAFNTBBCHE | |
| SCHEMBL9104578 | 0.80 | FNTA (0.35) | FNTAFNTBBCHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |