Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.69 |
| ▸ | CES1 | P23141 | 2/20 | 0.69 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953 | 1.00 | CES2 (0.69) | CES2CES1CA4CA1CA2 | |
| SCHEMBL5024814 | 0.92 | CES2 (0.60) | CES2CES1CA4CA1CA2 | |
| SCHEMBL41021 | 0.90 | CA1 (0.65) | CES2CES1CA1CA2MAPT | |
| SCHEMBL17080311 | 0.90 | CES2 (0.69) | CES2CES1CA1CA2NPC1 | |
| SCHEMBL719395 | 0.87 | CES2 (0.55) | CES2CES1CA4CA1CA2 | |
| SCHEMBL2761265 | 0.87 | CES2 (0.55) | CES2CES1CA4CA1CA2 | |
| SCHEMBL8823207 | 0.87 | CES2 (0.55) | CES2CES1CA4CA1CA2 | |
| SCHEMBL6682499 | 0.87 | CES2 (0.55) | CES2CES1CA4CA1CA2 | |
| SCHEMBL14856629 | 0.87 | CES2 (0.55) | CES2CES1CA4CA1CA2 | |
| SCHEMBL10518077 | 0.86 | CES2 (0.69) | CES2CES1CA4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 21760 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043642-B2 | Process for the purification of oligonucleotides | GENENTECH, INC. (US) | 2024-07-23 | — | — | US | claimed |
| WO-2024149093-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND CONJUGATE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2024-07-18 | — | — | WO | claimed |
| EP-4039690-B1 | A SUBSTANTIALLY DIASTEREOMERICALLY PURE PHOSPHORAMIDOCHLORIDATE, A METHOD AND A PHARMACEUTICAL COMPOSITION | EISAI R&D MAN CO LTD (JP) | 2024-07-17 | — | — | EP | claimed |
| CN-118345073-A | GalNAc derivative | 詹森生物制药有限公司 | 2024-07-16 | — | — | CN | claimed |
| EP-4396193-A1 | FUNCTIONALIZED N-ACETYLGALACTOSAMINE ANALOGS | Hongene Biotech Corporation (US) | 2024-07-10 | — | — | EP | claimed |
| US-12030907-B2 | Modified nucleoside phosphoramidites | Janssen Biopharma, Inc. (US) | 2024-07-09 | — | — | US | claimed |
| CN-118317970-A | Synthesis of 2' acetyl-ester protected nucleosides | 兆维生物科技公司 | 2024-07-09 | — | — | CN | claimed |
| CN-118290429-A | Preparation method of non-zolpidem intermediate and non-zolpidem | 山东百诺医药股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| US-20240218365-A1 | FORMULATION OF AN ANTISENSE OLIGOMER CONJUGATE | THE PROGERIA RESEARCH FOUNDATION, INC. | 2024-07-04 | — | — | US | claimed |
| EP-4392558-A1 | ANTISENSE OLIGONUCLEOTIDES HAVING ONE OR MORE ABASIC UNITS | Sarepta Therapeutics, Inc. (US) | 2024-07-03 | — | — | EP | claimed |
| EP-0058563-A1 | Lyophilized phosphorylated nucleosides | ens BIO LOGICALS INC. (CA) | 1982-08-25 | — | — | EP | claimed |
| US-4335240-A | Process for cyclization | ELI LILLY AND COMPANY (US) | 1982-06-15 | — | — | US | claimed |
| EP-0049072-A1 | Guanine compounds and their use for the preparation of anti-viral agents | SYNTEX (U.S.A.) INC. (US) | 1982-04-07 | — | — | EP | claimed |
| US-4310662-A | Nucleosidic phosphorylating agent and methods | GENENTECH, INC. (US) | 1982-01-12 | — | — | US | claimed |
| US-4302391-A | Unsymmetrical azetidinone aldehyde disulfides and process | ELI LILLY AND COMPANY (US) | 1981-11-24 | — | — | US | claimed |
| US-4293493-A | Azetidinone alcohol disulfides and process for cyclization | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | claimed |
| US-4293495-A | Symmetrical azetidinone aldehyde disulfides and process | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | claimed |
| EP-0035719-A2 | Process for producing modified inorganic polymers, their use in producing polynucleotides, and a reagent useful in these processes | UNIVERSITY PATENTS, INC. (US) | 1981-09-16 | — | — | EP | claimed |
| EP-0035255-A1 | Process for removing trityl blocking groups from 5'-O trityl nucleosides and oligonucleotides | UNIVERSITY PATENTS, INC. (US) | 1981-09-09 | — | — | EP | claimed |
| EP-0002322-A2 | Improved Triester process for the synthesis of oligonucleotides | GENENTECH, INC. (US) | 1979-06-13 | — | — | EP | claimed |