Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | PGK1 | P00558 | 1/20 | 0.43 |
| ▸ | PGK2 | P07205 | 1/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12820612 | 0.86 | GRIN2B (0.44) | ACP3ALDH1A1L3MBTL1PTPN5GAA | |
| SCHEMBL16499027 | 0.83 | SRC (0.46) | PGK1PGK2 | |
| SCHEMBL3722784 | 0.82 | F2R (0.43) | ALDH1A1L3MBTL1GAAATMGRIN2B | |
| SCHEMBL13840878 | 0.79 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1GAAATMGRIN2B | |
| SCHEMBL17007182 | 0.78 | KMT2A (0.49) | ACP3ALDH1A1PGK1PGK2 | |
| SCHEMBL14769155 | 0.78 | PGK1 (0.47) | ACP3PGK1PGK2 | |
| SCHEMBL1585625 | 0.77 | PGK1 (0.46) | ACP3PGK1PGK2 | |
| SCHEMBL1585621 | 0.77 | PGK1 (0.46) | ACP3PGK1PGK2 | |
| SCHEMBL16068085 | 0.72 | GRIN1 (0.55) | ALDH1A1L3MBTL1PARP1GAAATM | |
| SCHEMBL29134978 | 0.72 | GRIN1 (0.55) | ALDH1A1L3MBTL1PARP1GAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142690-A1 | Substituted piperidines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142690-A1 | Substituted piperidines | VHL, PIR, PIGO | ACP3 527/4885ALDH1A1 265/4885L3MBTL1 3725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.