Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 11/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106596 | 0.89 | P2RX1 (0.31) | APLNRP2RX4P2RX1 | |
| SCHEMBL9100730 | 0.89 | P2RX1 (0.31) | P2RX4P2RX1 | |
| SCHEMBL9102270 | 0.89 | P2RX1 (0.31) | P2RX4P2RX1 | |
| SCHEMBL9100209 | 0.88 | P2RX1 (0.30) | P2RX4P2RX1 | |
| SCHEMBL9100403 | 0.86 | KCNH2 (0.32) | — | |
| SCHEMBL9102910 | 0.86 | P2RX4 (0.31) | P2RX4P2RX1 | |
| SCHEMBL9101839 | 0.85 | TGFBR1 (0.31) | TGFBR1P2RX4 | |
| SCHEMBL9105492 | 0.82 | BCHE (0.34) | TGFBR1APLNRADRA1A | |
| SCHEMBL9104365 | 0.81 | P2RX4 (0.38) | P2RX4P2RX1 | |
| SCHEMBL18076900 | 0.80 | AGTR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |